Hubungan Tingkat Kepatuhan Penggunaan Obat terhadap Keberhasilan Terapi Hipertensi Di RSUD Waru Pamekasan pada Tahun 2024

Authors

Diah Arrizah Putri Program Studi Kedokteran, Fakultas Kedokteran, Universitas Wijaya Kusuma, Surabaya, Indonesia
Herni Suprapti Departemen Farmakologi, Fakultas Kedokteran, Universitas Wijaya Kusuma Surabaya

DOI:

Keywords:

Adherence, Hypertension, Therapeutic Success

Abstract

Background: Adherence is one of the definite requirements for for improving therapeutic effectiveness and the patient’s quality of life. Low adherence to prescribed antihypertensive medications is a major factor in uncontrolled hypertension. The patien’s disobedience to the use of drugs can be caused by boredom in taking hypertension medication, and patients often do not remember the time to take medication. Pameksan is one of the districts in East Java, the prevalence of hyeprtension patients in pamekasan has increased in 2017 around 23,16 %. Therefore, this study was conducted to determine whether there is a relationship between compliance with drug use and the success of hypertension therapy at RSUD Waru Pamekasan. Research Methods: This analytical observational study employed a cross-sectional design involving 32 hypertensive patients treated at Waru Pamekasan Hospital. Respondents were selected using a nonprobability sampling technique. The association between variables was analyzed using the chi-square test. Result of Research and Conclusion: The findings indicate a significant association between medication adherence and the therapeutic success of hypertension management among patients at Waru Pamekasan Hospital in 2024, supported by a p-value < 0.05.

References

AHA. (2017). Hypertension: The Silent Killer: Updated JNC-8 Guideline Recommendations. Alabama Pharmacy Association.

Ali, A. A., Abderraman, G. M., Tondi, Z. M. M., & Mahamat, H. A. (2019). Compliance of Hypertensive Patients with Antihypertensive Drug Therapy at The Renaissance Hospital of N’Djamena, Chad, HSPC Analys of Clinical Hypertension, (3), 47–51. https://doi.org/10.29328/journal.ach.1001019

Andria, K. M., Widati, S., & Nurmala, I. (2021). The Characteristics of Hypertension Patients at Puskesmas Waru, Pamekasan in 2018. Jurnal Promkes, 9(1), 11. https://doi.org/10.20473/jpk.v9.i1.2021.11-17.

Arini, N., & Ayuchecaria, N. (2019). Evaluasi Tingkat Kepatuhan Minum Obat Hipertensi pada Pasien Program Rujukan Balik Di Apotek Mitra Banjarmasin. Jurnal Ilmiah Ibnu Sina, 4(2), 410–419. https://doi.org/10.36387/JIIS.V4I2.359

Aryantiningsih, D. S., & Silaen, J. B. (2018). Kejadian Hipertensi Pada Masyarakat Di Wilayah Kerja Puskesmas Harapan Raya Pekanbaru. Jurnal Ipteks Terapan, 12(1), 64. https://doi.org/10.22216/jit.2018.v12i1.1483

Burnier, M. (2017). Drug adherence in hypertension. Pharmacological Research, 125. 142-149. https://doi.org/10.1016/j.phrs.2017.08.015

Chowdhury, R., Khan, H., Heydon, E., Shroufi, A., Fahimi, S., Moore, C., Stricker, B., Mendis, S., Hofman, A., Mant, J., & Franco, O. H. (2013). Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences. European heart journal, 34(38), 2940–2948.

https://doi.org/10.1093/eurheartj/eht295

Dipiro, J. T., Wells, B. G., Schwinghammer, T. L., & Dipiro C. V. (2015). Pharmacotherapy Handbook. Ninth Edition. McGraw-Hill Education.

Dwiutami, L., & Maheswari, J. (2013). Pola Perilaku Dewasa Muda Yang Kecenderungan Kecanduan Situs Jejaring Sosial. Jurnal Penelitian dan Pengukuran Psikologi, 2(1), 51-62. http://doi.org/10.21009/JPPP

Handono, N. (2024). Pengaruh Pemberian Air Rebusan Daun Seledri Terhadap Penurunan Tekanan Darah pada Penderita Hipertensi Grade 2 di Desa Lebak Pracimantoro. Jurnal Keperawatan GSH, 13(1), 9–15. https://doi.org/10.56840/jkgsh.v13i1.124

Ihwatun, S., Ginandjar, P., Saraswati, L. D., & Udiyono, A. (2020). Faktor-faktor yang Berhubungan dengan Kepatuhan Pengobatan pada Penderita Hipertensi di Wilayah Kerja Puskesmas Pudakpayung Kota Semarang Tahun 2019. Jurnal Kesehatan Masyarakat, 8(3), 352–359.

http://ejournal3.undip.ac.id/index.php/jkm

Istiqomah, H., Intiyani, R., & Widiastuti, T. C. (2022). The Relationship of Compliance Level of Drug Use and Therapy Success in Hypertension Patient At Outpatient Installation of PKU Muhammadiyah Hospital Sruweng. Urecol Journal, 719-728.

James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison, H. C., Handler, J., Lackland, D. T., Lefevre, M. L., Mackenzie, T. D., Ogedegbe, O., Smith, S. C., Svetkey, L. P., Taler, S. J., Townsend, R. R., Wright, J. T., Narva, A. S., & Ortiz, E. (2014). Evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the eighth joint national committee (JNC8). JAMA, 311(5), 507- 520. https://doi.org/10.1001/jama.2013.284427

Jumhani S. A., & Mutmainah, N. (2023). Hubungan Antara Kepatuhan Penggunaan Obat dengan Keberhasilan Terapi Antihipertensi Pada Pasien Geriatri di Rumah Sakit DR. Moewardi. Usadha: Journal of Pharmacy, 2(3), 361-372. https://doi.org/10.23917/ujp.v2i3.111

Kartikasari, D. S. S., & Pramatama, S. (2022). Literature review: Faktor-Faktor yang Mempengaruhi Tingkat Kepatuhan Pengobatan pada Pasien Hipertensi di Berbagai Wilayah Indonesia. Jurnal Pendidikan Tambusai, 6(2614–3097), 11665–11676. https://doi.org/10.31004/jptam.v6i2.4306

Kemenkes RI. (2018). Hasil Riset Kesehatan Dasar (Riskesdas) 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan Kementerian RI.

Meher, M., Pradhan, S., & Pradhan, S. R. (2023). Risk Factors Associated With Hypertension in Young Adults: A Systematic Review. Cureus, 15(4), e37467. https://doi.org/10.7759/cureus.37467

Ojangba, T., Boamah, S., Miao, Y., Guo, X., Fen, Y., Agboyibor, C., Yuan, J., & Dong, W. (2023). Comprehensive effects of lifestyle reform, adherence, and related factors on hypertension control: A review. Journal of clinical hypertension (Greenwich, Conn.), 25(6), 509–520.

https://doi.org/10.1111/jch.14653

PDHI. (2019). Konsensus Penatalaksanaan Hipertensi 2019. Jakarta: Indonesian Society of Hypertension.

Praningsih, S., Siswati, Maryati, H., & Khoiri, A. N. (2023). Peningkatan Pemahaman Tentang Pengendalian Tekanan Darah Melalui Kualitas Tidur dan Manajemen Stres di Desa Puton Kecamatan Diwek Kabupaten Jombang. DEDIKASI SAINTEK Jurnal Pengabdian Masyarakat, 2(2), 108–114.

https://doi.org/10.58545/djpm.v2i2.12

Pratiwi, R. I., & Perwitasari, M. (2017). Analisis Faktor-Faktor Yang Mempengaruhi Kepatuhan Pasien Hipertensi Dalam Penggunaan Obat di RSUD Kardinah. eJournal PoliTeknik Tegal, 2(1), 204-208.

Princewel, F., Cumber, S. N., Kimbi, J. A., Nkfusai, C. N., Keka, E. I., Viyoff, V. Z., Beteck, T. E., Bede, F., Tsoka-Gwegweni, J. M., & Akum, E. A. (2019). Prevalence and risk factors associated with hypertension among adults in a rural setting: the case of Ombe, Cameroon. The Pan African medical journal, 34, 147. https://doi.org/10.11604/pamj.2019.34.147.17518

Pristianty, L., Hingis, E. S., Priyandani, Y., & Rahem, A. (2023). Relationship between knowledge and adherence to hypertension treatment. Journal of public health in Africa, 14(Suppl 1), 2502. https://doi.org/10.4081/jphia.2023.2502

Sumiasih, H., Trilestari, & Utami, W. (2020). Hubungan Kepatuhan Minum Obat terhadap Keberhasilan Terapi pada Pasien Hipertensi di Puskesmas Prambanan Sleman Bulan Januari – Februari 2020. Cerata Jurnal Ilmu Farmasi, 11(1), 21-27. https://doi.org/10.61902/cerata.v11i1.95

Woodham, N., Taneepanichskul, S., Somrongthong, R., & Auamkul, N. (2018). Medication adherence and associated factors among elderly hypertension patients with uncontrolled blood pressure in rural area, Northeast Thailand. Journal of Health Research, 32(6), 449–458. https://doi.org/10.1108/JHR-11-2018-085.

WHO. (2023). Global report on hypertension: the race against a silent killer. Geneva: World Health Organization.